The airline is growing its UK fleet with an additional A320 family aircraft at its Bristol base, supporting around 400 jobs.
New services set to take off this summer include flights to Milan Linate from Manchester and Edinburgh and two new routes from Birmingham to Gibraltar and Bordeaux.
The additional aircraft in Bristol will support the launch of two new routes to Palermo in Italy and Almeria in Spain.
Seats are now on sale.
The new routes to Milan Linate have been enabled by the opening of a five aircraft base at Linate next spring, following approval by the European Commission.
The airline will also open a three-aircraft base at Rome Fiumicino from 30 March 2025, joining existing bases in Milan Malpensa and Naples.
Flights to Linate from Manchester and Edinburgh will take off for the first time on 30 March 2025 with flights up to seven days a week throughout the year.
It complements existing easyJet services to Milan Malpensa.
The airline will also increase frequencies from London Gatwick to Milan Linate from one to up to two daily departures.
From Birmingham, flights to Bordeaux will take off from 1 May and to Gibraltar from 1 June 2025.
New flights from Bristol to Almeria in Spain will launch on 24 June 2025 and operate twice a week on Tuesdays and Saturdays throughout the yea.,
A new summer route to Sicily’s capital Palermo will launch on 26 June 2025, with twice-weekly departures.
Tour operator easyJet holidays has launched thousands of packages across the new routes.
Ali Gayward, easyJet UK Country Manager, said: “Following another consecutive record summer, easyJet is continuing to grow in the UK next year with more aircraft, enabling us to offer an even greater choice of flights and package holidays.”
EasyJet serves 21 UK airports, offering 585 routes to 136 destinations from the UK to Europe and beyond.